This comprehensive issue will present the state-of-the-art knowledge on Legionnaire’s disease, coming from the country’s top experts. Articles are devoted to: History of Legionnaire’s Disease; Microbiology of Legionnaire’s Disease; Epidemiology of Legionnaire’s Disease; Clinical Features of Legionnaire’s Disease; Radiologic Features of Legionnaire’s Disease; Legionella Endocarditis; Legionnaire’s Disease Mimics; Legionnaire’s disease in Compromised Hosts; Legionnaire’s Disease in HIV; Travel-Related Legionnaire’s Disease; Legionnaire’s Outbreaks; Laboratory Diagnosis of Legionnaire’s Disease; and Antimicrobial therapy of Legionnaire’s Disease.